相关实验视频

Updated: Jul 14, 2026

Isolation of Nuclei from Flash-Frozen Liver Tissue for Single-Cell Multiomics

Isolation of Nuclei from Flash-Frozen Liver Tissue for Single-Cell Multiomics

Published on: December 9, 2022

通过单细胞RNA测序揭示的肝癌细胞类型的动态:进步和挑战

Wenxin Li¹, Huisi He², Hongyang Wang³

¹Third Affiliated Hospital of Naval Medical University (Second Military Medical University), National Center for Liver Cancer, Shanghai, 200438, China; Department of Clinical Laboratory Medicine, Third Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai, 200438, China.

|December 17, 2024

概括

单细胞RNA测序揭示了肝癌的发生.

科学领域:

在瘤学瘤学.
基因组学就是基因组学.
分子生物学分子生物学

背景情况:

肝癌是全球主要的健康问题.
了解细胞动态对于有效治疗至关重要.

研究的目的:

审查用于肝癌研究的单细胞RNA测序方面的进展.
突出了解癌症异质性和瘤微环境 (TME) 的见解.

主要方法:

单细胞RNA测序 (scRNA-seq) 技术.
在单细胞分辨率下分析细胞异质性和TME.

主要成果:

scRNA-seq为肝癌的发展和进展提供了深入的见解.
确定了关键的分子驱动因素和表型景观.
功能细胞子集和TME多样性的详细映射.

结论:

scRNA-seq对于开发向治疗和预后工具至关重要.
了解瘤发作到进展的进展有助于个性化治疗策略.

关键词:

异质性异质性异质性肝癌是一种肝癌.精准医学是一门精准的医学.单细胞RNA测序的一个细胞.瘤微环境是一个微环境.

更多相关视频

Author Spotlight: Exploring Strategies for Successful Immune Response Against Tumors

Author Spotlight: Exploring Strategies for Successful Immune Response Against Tumors

Published on: August 16, 2024

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

相关概念视频

RNA-seq

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases.
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...