增长调节为复杂的三维外骨的形态发生带来了模块化
1Research Center for Integrative Evolutionary Science, The Graduate University for Advanced Studies, SOKENDAI, Hayama, Kanagawa 240-0193, Japan.
Proceedings. Biological sciences
|December 17, 2024
概括
多种关节动物的外生,如甲虫的角,由非均的表皮生长形成. 这项研究揭示了形态原分布如何指导这种增长,创造复杂的3D结构,并提供了进化形态学的见解.
科学领域:
- 发育生物学 发展生物学
- 进化形态学 进化形态学
- 生物物理学的生物物理.
背景情况:
- 关节动物的附属物,如甲虫的角,表现出不同的3D形态.
- 这些结构是由发育过程中表皮生长不均而产生的.
- 将形态原体分布与复杂形状生成联系在一起的精确机制仍然不清楚.
研究的目的:
- 研究表皮生长调节与由此产生的3D结构之间的关系.
- 理论上建模平面表皮如何形成复杂的形状,如甲虫的角.
主要方法:
- 用一个演式生长模型来模拟表皮形态发生.
- 该模型将形态原分布与非均的组织生长相关联.
- 探索多个形态原体的异常表达如何影响形状的产生.
主要成果:
- 证明多个形态原体的异常表达可以产生多样化的3D结构.
- 展示了简单形状的灵活融合,以模拟复杂的关节动物外生.
- 该模型成功生成了模仿甲虫角和其他复杂结构的形状.
结论:
- 通过受调节的非均表皮生长的形态发生提供了发育稳定性和模块化.
- 这种机制为理解各种节肢动物形态的演变提供了一个框架.
- 研究结果提供了关于节肢动物进化多样化的发展基础的见解.
相关概念视频
Morphogenesis
26.2K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
26.2K
Gastrulation
56.6K
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
56.6K
Bone Remodeling
38.1K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.1K
Changes in the Appendicular Skeleton with Age
1.8K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
1.8K
Microbial Morphologies
1
Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
1
Whole Body Regeneration
3.3K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
3.3K


