急性肉症:医院住院期间对其发病率和肌肉参数变化的系统审查和元分析
Luke Aldrich1, Theocharis Ispoglou1, Konstantinos Prokopidis2
1Carnegie School of Sport, Leeds Beckett University, Headingley Campus, Leeds, UK.
Journal of cachexia, sarcopenia and muscle
|December 17, 2024
概括
急性皮症影响了18%的住院患者,肌肉质量显著下降. 目前的评估可能不足以诊断这种情况,影响康复和生活质量.
科学领域:
- 老年学是一门学科.
- 临床医学 临床医学
- 肌肉生理学 肌肉生理学
背景情况:
- 剧烈的萨尔科佩尼亚,定义为萨尔科佩尼亚<6个月,可在急性疾病/伤害之后出现.
- 它可能是慢性肉症的前身,影响患者的康复和生活质量.
- 了解其在住院期间的发展和评估是有限的.
研究的目的:
- 为了确定住院患者急性肉症的发病率.
- 在住院期间检查肌肉参数 (质量,强度,功能) 的变化.
- 确定影响这些变化的因素.
主要方法:
- 88篇论文的系统审查和叙事综合.
- 关于手握强度 (HGS),直腿骨横截面积 (RFCSA) 和肌肉功能测试的元分析.
- 医院住院时间 (LoS) 和年龄的元回归;对于HGS考虑的性别.
主要成果:
- 在住院期间,急性肉类的综合发病率为18%,在ICU创伤患者中最高 (59%).
- 肌肉质量 (RFCSA) 在3-21天内减少了16.5%,这是LoS预测的.
- HGS和一些肌肉功能测试显示在住院期间对急性变化的敏感性有限.
结论:
- 在临床环境中对急性肉症的评估具有挑战性,并且可能被诊断不足.
- 肌肉质量和质量指数可能是住院患者肌肉健康的更可靠指标.
- 需要进一步的研究来完善急性肉症的诊断标准.
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