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细菌和宿主化维持IgA稳态,以限制小鼠的肠道炎症

Chao Lei1,2, Chao Luo3,4, Zhishan Xu5,6

  • 1Division of Immunotherapy, Department of Surgery, University of Louisville, Louisville, KY, USA. chao.lei@louisville.edu.

Nature microbiology
|December 17, 2024
PubMed
概括

宿主和细菌的化对肠道健康至关重要. 改变的fucosylation增加了对炎症性肠病 (IBD) 的易感性,并影响了免疫反应,突出了它在维持肠道免疫恒常性中的作用.

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Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
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