在拔牙前使用抗生素是否能减少手术后不良结果?
Darshini Ramasubbu1, Jonathan Lewney2
1Dublin Dental University Hospital, Trinity College Dublin, Dublin, Republic of Ireland. RAMASUBD@TCD.IE.
Evidence-based dentistry
|December 17, 2024
概括
这项研究发现,在老年牙科患者的抗生素预防和提取后并发症之间没有联系. 抗生素的使用没有增加或减少口腔感染,口腔干燥或牙科手术后发烧的风险.
科学领域:
- 在口腔外科手术.
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 拔牙后的并发症是牙科手术中的一个问题.
- 抗生素预防是常用的,但其对结果的影响需要澄清.
研究的目的:
- 调查抗生素预防与牙提取后手术后并发症之间的关联.
- 为了确定使用抗生素是否会增加或减少口腔感染,口腔干燥或发烧等风险.
主要方法:
- 对269,003名牙科患者进行了回顾性队列研究.
- 在拔牙之前,对抗生素处方 (干预) 与没有处方 (比较器) 的分析.
- 多变量后勤回归模型来评估与提取后并发症的关联,在7天内.
主要成果:
- 在385,880次牙科诊所中,有31.8%的人被处方抗生素.
- 糖尿病是一个显著的修饰因素;对于非糖尿病患者,抗生素增加了并发症的几率.
- 总的来说,在整个队列中,没有发现抗生素预防和提取后并发症之间的统计学意义上的关联.
结论:
- 在这组老年人中,牙提取前的抗生素预防与术后并发症的增加或减少风险无关.
- 研究结果表明,日常抗生素使用可能不必对所有接受牙科拔牙的患者进行.
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