在I型脊柱肌肉缩中神经肌肉退化的机动池选择性在人类和小鼠之间保持不变

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Justin C Lee1,2, Wendy K Chung3, David J Pisapia4

  • 1Center for Motor Neuron Biology and Disease, Columbia University Medical Center, 630 W. 168th St., New York, NY 10032, United States.

Human molecular genetics
|December 18, 2024
PubMed
概括

脊椎肌肉缩 (SMA) 选择性地损害运动神经元. 这项研究揭示了运动单元退化中的显著差异,表明了可能是治疗点的特定抵抗机制.

关键词:
运动神经元 运动神经元发动机单元的发动机单元.神经退行症的神经退行症神经肌肉的神经肌肉脊柱肌肉缩 脊柱肌肉缩 脊柱肌肉缩

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