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在没有手术干预的情况下,在有症状的慢性腹腔内血瘤中使用特兰克萨姆酸

Raghavendra Nayak¹, Ashwin Pai¹, Arjun Anand¹

¹Department of Neurosurgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education (MAHE) Manipal, Karnataka, India.

Neurology India

|December 18, 2024

概括

特兰胺酸有效地治疗高风险患者的症状性慢性腹腔内血瘤 (CSDH). 这种保守的方法为手术提供了一个可行的替代方案,显示出显著的血液瘤解脱,没有复发或重大并发症.

科学领域:

神经外科神经外科
药理学药理学是指药理学的学科.
放射学放射学是一门学科.

背景情况:

症状性慢性腹腔内血瘤 (CSDH) 的标准治疗包括洞穴疏散.
对于具有高手术风险的CSDH患者,缺乏确定的实践指南.

研究的目的:

评估特兰胺酸作为症状性CSDH的唯一治疗方法的疗效.
为了分析血瘤解脱,复发和并发症的患者管理与tranexamic 酸.

主要方法:

一组22名入院患者有症状的CSDH,接受了口服松酸 (250毫克每天三次) 的治疗.
治疗持续到血液瘤消失,每月进行一次随访CT扫描.
收集和分析了血液瘤体积,分辨率和复发的数据.

主要成果:

治疗持续时间中位数为60天,使血液中位数从74毫升减少到2毫升.
平均中线偏移从15毫米减少到0毫米,这表明有显著的改善.
没有观察到血液瘤的进展或复发;没有发生诸如血栓栓塞等重大并发症.

结论:

当手术具有风险或不可行时,特兰胺酸为症状性CSDH提供了有效的替代管理.
这种保守的治疗可以考虑在没有立即威胁生命的患者,避免手术干预.

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