对肺部领域参与Sjögren病的分析
Marta Madej1, Krzysztof Proc2, Piotr Wawryka2
1Department and Clinic of Rheumatology and Internal Medicine, Wroclaw Medical University, Wroclaw, Poland.
Therapeutic advances in musculoskeletal disease
|December 18, 2024
概括
肺部干扰在Sjögren患者中很常见.
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
背景情况:
- 斯约格伦病 (SjD) 可以影响呼吸系统,间歇性肺病 (ILD) 是一个严重的表现.
- 欧拉Sjögren综合征 (SS) 疾病活动指数 (ESSDAI) 肺部域评估了SjD中的呼吸道参与.
研究的目的:
- 用高分辨率计算机断层扫描 (HRCT) 来评估SjD患者的呼吸系统参与和ILD发生情况.
- 确定免疫标志物,吸烟和年龄对呼吸道干扰和SjD中的ILD的影响.
主要方法:
- 进行了一项单中心,注册,队列研究.
- 对患有SjD和肺部域参与的患者 (n=64) 进行了免疫学标志物和HRCT发现的分析.
主要成果:
- 在299名SjD患者中,有64名肺部参与被确定,干咳和慢性咳是最常见的.
- 53%的肺部干扰患者在HRCT上有ILD;年龄较大和类风湿因子阳性更为常见.
- 肺部感染类型和免疫学概况,炎症标志物,年龄或吸烟之间没有发现相关性.
结论:
- 肺部域参与在SjD患者中很常见,呈现出各种临床症状.
- 呼吸系统参与的异质性需要针对SjD患者个性化治疗策略.
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