在美国初级保健患者中保存比率损伤螺旋测量诊断出慢性阻塞性肺病
Alexander Evans1, Yasir Tarabichi2, Wilson D Pace3,4
1Observational and Pragmatic Research Institute, Singapore, Singapore.
Pragmatic and observational research
|December 18, 2024
概括
保留比率受损螺旋计 (PRISm) 影响了近四分之一被诊断患有COPD的初级保健患者. 这些患者经历了显著的呼吸道症状和肺气,尽管不符合COPD阻塞标准.
科学领域:
- 肺部医学 肺部医学
- 呼吸系统健康 呼吸系统健康
- 临床流行病学临床流行病学
背景情况:
- 保留比率受损螺旋计 (PRISm) 描述了不符合COPD螺旋计标准的呼吸系统症状患者.
- 这种人群可能会从呼吸系统管理和治疗中受益.
- 了解PRISm的流行率和特征对于初级保健至关重要.
研究的目的:
- 为了确定PRISm在美国首要护理中患有COPD的患者的患病率.
- 描述PRISM患者的人口,临床和CT扫描特征.
- 评估PRISm作为肺功能下降的预测指标.
主要方法:
- 使用美国APEX COPD注册表进行的观察性注册表研究 (年龄在35岁以上的患者).
- 从电子健康记录和问卷收集的数据.
- 多变量后勤回归用于分析PRISM预测因素和结果.
主要成果:
- 在初级保健患者中,有COPD诊断的PRISm患病率为23.6%.
- PRISM患者更有可能是女性,年轻,BMI较高,并且比符合螺旋计标准的COPD患者更有可能是非裔美国人或西班牙裔患者.
- 在PRISm患者的CT扫描中,肺气更常见,这些患者也报告了显著的呼吸系统症状,但PRISm没有预测肺功能下降.
结论:
- 在被诊断为COPD的初级保健患者中,几乎有四分之一的患者表现出PRISm.
- PRISM患者出现显著的呼吸道症状和肺气,需要进一步调查和管理.
- 在这个队列中,PRISM状态并不能预测未来的肺功能下降.
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