对儿科患者处方和分发口服抗生素口味不佳的挑战:与全科医生和药剂师进行定性访谈研究
Ayat Elgammal1,2, Joseph Ryan3, Colin Bradley3
1Pharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cork, Ireland.
Exploratory research in clinical and social pharmacy
|December 18, 2024
概括
味道不佳的液体抗生素导致儿童没有完成治疗,冒着疾病复发和抗菌素耐药性的风险. 改善医疗保健提供者和家长的抗生素风味和意识对于更好的遵守至关重要.
科学领域:
- 药理学和制药学 药理学和制药学
- 儿科医学 儿科医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在儿童中,口服液体抗生素的口感不佳是治疗坚持的重要障碍.
- 由于味道问题导致不坚持可以导致治疗失败,疾病复发,并增加抗菌素耐药性.
- 了解医疗保健专业人员对处方和发放挑战的看法至关重要.
研究的目的:
- 调查全科医生和社区药剂师对儿童口服液体抗生素的经验和挑战.
- 探索难以品味的抗生素配方对儿科患者和医疗保健系统的影响.
- 确定克服小儿抗生素治疗中可口性挑战的策略.
主要方法:
- 与全科医生和社区药剂师进行了半结构化访谈.
- 采访通过在线视频会议平台进行.
- 用专题分析分析了定性数据.
主要成果:
- 出现了三个主要主题:处方医生/药剂师所面临的挑战,糟糕的口感的影响以及克服这些问题的策略.
- 挑战包括影响抗生素选择的因素,与家长的讨论以及配方特征.
- 影响涉及患者结果 (不遵守,复发) 和卫生系统后果,意识和咨询被确定为关键解决方案.
结论:
- 提高医疗保健专业人员和家长的口感意识对于改善抗生素坚持是必不可少的.
- 建议开发更易于食用的口服液体抗生素配方.
- 解决可口性问题可以改善处方和药物服用实践.
相关概念视频
Drug Delivery: Enteral Route
377
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
377
Factors Affecting Drug Response: Overview
1.8K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
1.8K
Prescription, Nonprescription and Orphan Drugs
687
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
687
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry
174
Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
174
Routes of Drug Administration: Enteral
3.2K
Medications can be administered through the enteral route using liquids, capsules, or tablets.
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
3.2K
Tonsillitis II: Management
103
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
103


