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在年轻健康成年人中,BAG-3突变扩展性心肌病与左心室非紧缩

Yash B Patel1, Wadie David2, Milan Terzic1

  • 1Department of Internal Medicine, Trinity Health Ann Arbor, Michigan, USA.

JACC. Case reports
|December 18, 2024
PubMed
概括

一个BAG3基因突变导致34岁男子心力衰竭和左心室非紧缩. 这一案例凸显了非缺血性心肌病的遗传因素.

关键词:
心肌病性心脏病 - 心肌病性心脏病遗传疾病 遗传疾病遗传学 遗传学 遗传学 是一个

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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