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Carlos Alexandre Ferreira de Oliveira¹, Livia Maria Borges Amaral¹, José Pedro Cassemiro Micheleto¹

¹Faculty of Medicine, Federal University of Alagoas, Maceió, Brazil.

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

|December 18, 2024

概括

这项研究发现,在COVID-19和没有COVID-19的透析患者之间,在肉症风险或炎症标志物上没有显著差异. 在一组患者中观察到甲状腺上腺激素 (PTH) 升高,这表明该患者群体中存在复杂的相互作用.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
传染性疾病传染性疾病
内分泌学在内分泌学.

背景情况:

糖尿病,肥胖和慢性病 (CKD) 对肌肉骨健康产生负面影响.
这些情况增加了2019年冠状病毒病 (COVID-19) 严重后果的风险.

研究的目的:

在透析患者中调查COVID-19状态和肉症风险之间的关联.
在这个人群中检查与COVID-19相关的炎症标志物和身体成分.

主要方法:

32名透析患者的横截面研究,按COVID-19状态划分.
评估了炎症标志物 (IL-1β,IL-6,IL-8,TNF-α),肉症风险 (SARC-F,生物阻抗,肌肉强度) 和副甲状腺激素 (PTH).

主要成果:

在COVID-19阳性和阴性组之间,炎症标志物或肉症风险没有显著差异.
身体构成和肌肉力量是可比的,除了一个组的PTH水平升高 (p=0.008).

结论:

炎症和皮症之间缺乏明确的关联可能是由于糖尿病,慢性病和肥胖症患者的先前存在的炎症状态.
升高的PTH水平是区分两组的主要实验室发现.

关键词:

根据COVID-19的情况,慢性脏疾病慢性脏疾病在糖尿病中,糖尿病是血糖性糖尿病.血液透析是血液透析的方法之一.这是一种炎症炎症炎症炎症.肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖

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