维生素B在健康衰老和疾病中的作用
Kathleen Mikkelsen1, Maria Trapali2, Vasso Apostolopoulos3
1Institute for Health and Sport, Victoria University, Werribee, VIC, Australia.
Sub-cellular biochemistry
|December 18, 2024
概括
最佳的维生素B水平对于老年人来说至关重要,可以预防与老化相关的神经认知问题,炎症和心血管疾病. 保持充足的B族维生素摄入量有助于整体健康,并减轻与年龄相关的健康风险.
科学领域:
- 营养科学 营养科学
- 老年学是指老年学的学科.
- 生物化学 生物化学
背景情况:
- 维生素B组合物 (B1,B2,B5,B6,B9,B12) 对能量代谢,DNA维护和免疫功能至关重要.
- 不足够的维生素B水平与神经认知问题,免疫失衡和炎症有关.
- 由于B族维生素缺乏,老年人面临心血管疾病,中风,认知衰退和神经退行症的风险增加.
研究的目的:
- 探索维生素B在衰老过程中的广泛作用.
- 突出维生素B缺乏对与年龄相关的健康问题的影响.
- 强调在老年人群中保持最佳维生素B水平的潜在好处.
主要方法:
- 关于维生素B的功能和衰老中的缺陷的文献综述.
- 分析B族维生素与与年龄相关的生理变化 (糖化,线粒体,氧化应激) 之间的关系.
- 讨论维生素B状态对预防与年龄有关的疾病的影响.
主要成果:
- 维生素B缺乏会加剧与年龄相关的疾病,如心血管疾病,认知障碍和神经退行症.
- 糖化,线粒体和氧化应激的变化有助于在衰老中与维生素B相关的问题.
- 最佳的维生素B水平可能会对各种与年龄相关的疾病产生保护作用.
结论:
- 确保足够的维生素B摄入量对于支持老年人的健康至关重要.
- 维生素B在减轻与衰老相关的风险方面发挥着关键作用,包括神经退行和心血管问题.
- 对老年人补充维生素B的策略进行进一步的研究是有必要的.
关键词:
年龄化 衰老 衰老科巴胺 (cobalamin) 是一种可胺.叶酸是什么意思?叶酸是什么意思?尼阿酸尼阿酸是最重要的.皮里多克辛 (Pyridoxine) 是一种素.利博弗拉维因是一种黄素.提氨酸是一种氨酸.维生素B 维生素B是一种维生素.更多相关视频
11:44Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
Published on: January 19, 2022
2.4K
08:52Measurement of Protein Turnover Rates in Senescent and Non-Dividing Cultured Cells with Metabolic Labeling and Mass Spectrometry
Published on: April 6, 2022
3.4K
相关概念视频
01:25Role of Vitamins in Maintaining Bone Health
3.1K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.1K
01:30Vitamins
553
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
553
01:37Mitochondria
10.7K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
10.7K
01:19The Effect of Aging on Tissues
2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
01:23Role of Skin in Vitamin D Synthesis
5.0K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.0K
01:20Lifestyle Factors and Health
34
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
34