改善认知障碍老年人参与研究的策略:系统性审查
Lucinda Swan1,2, Slavica Kochovska3,4, Nola Ries5
1School of Medicine and Nursing Sydney, University of Notre Dame Australia, Darlinghurst, NSW, Australia.
The Gerontologist
|December 18, 2024
概括
将认知障碍的老年人纳入临床研究的策略显示出有希望. 对招聘和同意的定制方法是有效的,但需要更多高质量的研究.
科学领域:
- 老年学是指老年学的学科.
- 临床研究方法论 临床研究方法论
- 认知障碍研究 认知障碍研究
背景情况:
- 认知障碍的老年人在临床研究中表现明显不足.
- 这种代表性不足限制了研究结果对这一弱势群体的概括性.
- 需要有效的战略来加强他们的包容和参与.
研究的目的:
- 系统地审查关于支持认知障碍老年人参与和参与临床研究的战略的证据.
- 为这一群体确定有效的招聘和同意方法.
- 评估不同包容战略的结果.
主要方法:
- 对已发表的报告进行系统审查 (PROSPERO CRD42020212092).
- 在多个日期 (2020-2024) 中搜索了5个数据库.
- 使用苏格兰大学间指南网络方法检查清单评估偏见风险.
主要成果:
- 包括12项涉及4208名参与者的研究 (平均年龄为78.3岁).
- 社区外展和人口查的招聘率高于初级保健转诊率.
- 记忆辅助器提高了知情同意能力,而非正式的同意方法比正式的方法更成功.
结论:
- 有针对性,量身定制和多方面的招聘和同意策略显示出增加认知障碍老年人的包容性的潜力.
- 需要更高质量的研究来验证这些有希望的发现.
- 对参与者保留和不良事件的进一步调查是有必要的.
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