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Updated: Jun 4, 2025

Simultaneous Quantification of Anti-vector and Anti-transgene-Specific CD8+ T Cells Via MHC I Tetramer Staining After Vaccination with a Viral Vector
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Simultaneous Quantification of Anti-vector and Anti-transgene-Specific CD8+ T Cells Via MHC I Tetramer Staining After Vaccination with a Viral Vector

Published on: November 28, 2018

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免疫型MHC-I分析和免疫性测试确定Tcj2是查加斯病mRNA疫苗的新候选者

Leroy Versteeg1,2, Rakesh Adhikari1, Gonteria Robinson1

  • 1Texas Children's Hospital Center for Vaccine Development, Department of Pediatrics, Division of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America.

PLoS pathogens
|December 18, 2024
PubMed
概括

研究人员确定Tcj2为查加斯病的有希望的疫苗候选人. 用Tcj2免疫小鼠产生了强烈的免疫反应,减少了寄生虫的复制,并显示了针对慢性查加斯性心肌病的新型mRNA疫苗的潜力.

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