动态子谱伴随着Pseudomonadota能量代谢的多样化
Sophie-Carole Chobert1, Morgane Roger-Margueritat1, Laura Flandrin1
1Univ. Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, Grenoble 38000, France.
The ISME journal
|December 18, 2024
概括
伪虫细菌进化了多样化的子系统,使其能够适应不断变化的氧气水平. 这种代谢灵活性推动了它们在各种环境中的生态成功和多样化.
科学领域:
- 微生物的新陈代谢
- 细菌进化的过程
- 生物地质化学生物地质化学
背景情况:
- 伪冠状虫是一种非常丰富和多样化的细菌类.
- 它的进化起源与大氧化事件相吻合.
- 要了解它的成功,需要研究适应不同氧度的适应性.
研究的目的:
- 为了阐明Pseudomonadota.的进化历史.
- 调查异oprenoid胺在它们的代谢多功能性中的作用.
- 了解它们如何适应不同氧气环境.
主要方法:
- 对子生物合成途径的遗传学分析.
- 关于 Pseudomonadota 的比较基因组学.
- 重建祖先的代谢能力.
主要成果:
- 迷失了menaquinone (MK),而在Pseudomonadota的祖先中出现了ubiquinone (UQ).
- 在最后一个共同的祖先中存在O2依赖性和O2独立性UQ通路.
- 独立于O2的途径促进了MK/rhodoquinone的重新获取,促进了厌氧/选择性厌氧代谢.
结论:
- Pseudomonadota 的生态成功与其动态的子谱系有关.
- 这种适应性使得不同的殖民化,氧气水平波动.
- 子通路的演变对于Pseudomonadota的多样化至关重要.
相关概念视频
Microbial Nutrition
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
Metabolism of Chemolithotrophs
1
Chemolithotrophs are microorganisms that obtain energy by oxidizing inorganic molecules such as hydrogen gas (H₂), ammonia (NH₃), reduced sulfur compounds (H₂S, S²⁻), and ferrous iron (Fe²⁺). Unlike heterotrophic organisms that rely on organic carbon, chemolithotrophs transfer electrons from these inorganic donors to the electron transport chain (ETC), generating a proton motive force (PMF) that drives ATP synthesis through oxidative phosphorylation.
1
Anoxygenic Photosynthesis
Anoxygenic photosynthesis is a phototrophic process that captures light energy to drive carbon fixation without producing molecular oxygen. Unlike oxygenic photosynthesis, which utilizes water as an electron donor and releases oxygen, anoxygenic phototrophs use alternative electron donors such as hydrogen sulfide (H₂S), elemental sulfur (S⁰), or thiosulfate (S₂O₃²⁻). This process is carried out by diverse groups of bacteria, including purple bacteria, green...
Other Glycolytic Pathways
The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...
Electron Transport Chain: Complex III and IV
7.0K
During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
7.0K


