相关实验视频
Updated: Jun 4, 2025

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
18.8K
新生儿高胰岛素血糖低血症的管理:九年来的趋势
Sabitha Sasidharan Pillai1, Meghan E Fredette1, Joshua Ray Tanzer2
1Division of Pediatric Endocrinology, Hasbro Children's Hospital, The Warren Alpert Medical School of Brown University, Providence, RI.
Rhode Island medical journal (2013)
|December 18, 2024
概括
对超胰岛素性低血糖症 (HH) 的二氧化的使用发生了变化,发病时间延迟,早产婴儿和妊娠年龄 (SGA) 较小的婴儿的使用减少. 肺高血压 (PHT) 发生在12.5%的接受治疗的婴儿中,特别是那些早产或SGA.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 新生儿科学 新生儿科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 对超胰岛素性低血糖症 (HH) 的增加使用氧化物与报告的严重副作用增加有关,特别是肺高血压 (PHT).
- 了解二氧化的安全概况至关重要,特别是在脆弱的婴儿群体中.
研究的目的:
- 分析HH的婴儿对氧化物处方模式的变化.
- 调查二氧化使用与婴儿PHT发展之间的关联,重点是早产和妊娠年龄 (SGA) 婴儿.
主要方法:
- 对被诊断患有HH并由儿科内分泌学评估的婴儿的回顾性图表审查.
- 对二氧化开始时间,使用率和PHT发育的分析,按妊娠年龄和SGA状态分层.
主要成果:
- 在2017年6月以后的早产和SGA婴儿中,以及在2020年5月以后的所有婴儿中,diazoxide的开始被推迟.
- 在2020年5月之后,接受二氧化的SGA婴儿比例显著下降.
- 肺高血压 (PHT) 发生在12.5%的接受过氧化治疗的婴儿中,早产/SGA婴儿的发病率更高,以及孕前的母亲所产生的婴儿.
结论:
- 对HH的氧化物处方模式已经发展,在高风险婴儿群体 (早产,SGA) 中使用延迟和减少的特征.
- 肺高血压是治疗二氧化的婴儿的一个重要问题,特别是那些早产,SGA或暴露于孕前的婴儿.
相关概念视频
Hypoglycemia and Glucagon
150
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
150
Pathophysiology of Diabetes
862
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
862
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Insulin: Dosing Regimen and Adverse Effects
142
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
142
Diabetes Mellitus: Overview and Type I Subtype
2.4K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.4K
Diabetes: Management and Pharmacotherapy
234
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
234

