Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

EnhancerDB 2.0: a comprehensive cross-species enhancer atlas.

Molecular biology and evolution·2026
Same author

The application effect of mini midline catheters in intravenous therapy for neurology patients: real-world evidence from eastern China.

Frontiers in medicine·2026
Same author

The Application of Nanomaterials in the Detection of Liver Cancer Biomarkers.

International journal of nanomedicine·2026
Same author

Identification of RRM2 as a key regulator of malignant epithelial cells in gastric cancer through single‑cell transcriptomics.

Oncology reports·2026
Same author

Molecular taxonomy and spatial organization define neuronal subtypes in the mouse inferior colliculus.

iScience·2026
Same author

Development of an injectable supramolecular hydrogel system for prolonged and controlled insulin release in diabetes management.

International journal of biological macromolecules·2026

相关实验视频

Updated: Jun 4, 2025

Reusable Single Cell for Iterative Epigenomic Analyses
10:28

Reusable Single Cell for Iterative Epigenomic Analyses

Published on: February 11, 2022

1.3K

scEccDNAdb:用于人类和小鼠的集成单细胞eccDNA资源.

Wenqing Wang1, Xinyu Zhao1, Tianyu Ma1

  • 1School of Life Sciences and Engineering, Southwest Jiaotong University, No.111, North 1st Section of Second Ring Road, Chengdu, Sichuan 610031, China.

Database : the journal of biological databases and curation
|December 18, 2024
PubMed
概括

一个新的数据库scEccDNAdb为分析单细胞异染色体圆形DNA (eccDNA) 提供了全面的资源. 它提供数以百万计的eccDNA条目和分析工具,以推进细胞异质性和功能的研究.

更多相关视频

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells
08:30

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

Published on: January 7, 2020

12.8K
Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing
10:44

Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing

Published on: March 23, 2022

4.1K

相关实验视频

Last Updated: Jun 4, 2025

Reusable Single Cell for Iterative Epigenomic Analyses
10:28

Reusable Single Cell for Iterative Epigenomic Analyses

Published on: February 11, 2022

1.3K
Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells
08:30

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

Published on: January 7, 2020

12.8K
Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing
10:44

Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing

Published on: March 23, 2022

4.1K

科学领域:

  • 基因组学就是基因组学.
  • 分子生物学分子生物学
  • 生物信息学是一种生物信息学.

背景情况:

  • 超染色体循环DNA (eccDNA) 在真核生物中普遍存在,但由于有限的高通量方法,单细胞分析具有挑战性.
  • 在单细胞水平上了解eccDNA对于了解细胞异质性,进化和功能至关重要.

研究的目的:

  • 为单细胞eccDNA分析开发一个全面的数据库.
  • 为研究eccDNA.DNA的研究人员提供可访问的工具.

主要方法:

  • 使用单细胞全基因组测序数据构建了scEccDNAdb.
  • 整合了来自人类和小鼠样本的3,195,464个单细胞eccDNA条目.
  • 包括广泛的注释和9个在线分析/可视化工具.

主要成果:

  • scEccDNAdb包含一个大规模的单细胞eccDNA数据集合.
  • 标注涵盖瘤基因,增强剂,调节元件,遗传变异和染色质特征.
  • 在线工具可以从用户数据中生成出版品质的数据.

结论:

  • scEccDNAdb是单细胞eccDNA分析的一个有价值的,全面的资源.
  • 该数据库支持跨多种细胞类型,组织和物种的研究.
  • 有助于更深入地了解eccDNA在细胞过程中的作用.