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CLK1 激活 YAP 促进肝脏内胆血管癌发生

Shuai Xue1,2, Xiangzheng Chen1, Guoteng Qiu1

  • 1Division of Liver Surgery, Department of General Surgery and Laboratory of Liver Surgery, West China Hospital, Sichuan University, Chengdu, China.

Cancer research
|December 18, 2024
PubMed
概括

类似Cdc2的激酶1 (CLK1) 通过激活Hippo-YAP通路来驱动肝内胆管癌 (ICC) 的生长. 抑制YAP显示出治疗CLK1驱动的ICC的前景.

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