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FT-NIR模型用于预测无二氧化片涂层中的薄膜质量参数

Filip Gorachinov1, Monika Koviloska2, Katerina Tnokovska2

  • 1Research & Development, Alkaloid AD-Skopje, Blvd. Aleksandar Makedonski 12, 1000, Skopje, North Macedonia; Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy, Institute of Pharmaceutical Technology, Mother Theresa 47, 1000 Skopje, North Macedonia.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|December 18, 2024
PubMed
概括

福里埃变换近红外 (FT-NIR) 光谱学有效监测药物片的涂层厚度和颜色进展. 这种非破坏性方法有助于药品制造的质量控制和流程优化.

关键词:
在FT-NIR中.薄膜的厚度 薄膜的厚度多变量分析多变量分析.过程分析技术 过程分析技术没有二氧化的薄膜涂层.

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相关概念视频

IR Frequency Region: Fingerprint Region01:03

IR Frequency Region: Fingerprint Region

IR spectra are divided into two main regions: the diagnostic region and the fingerprint region. The diagnostic region of the spectrum lies above 1500 cm−1. The absorptions resulting from single-bond vibrations of the N–H, C–H, and O–H stretch at higher wavenumbers and appear on the left side of the spectrum. The stretching absorptions of the C≡C and C≡N occur between 2100–2300 cm−1. In contrast, those arising from stretching absorptions of the C=O, C=N, and C=C occur between 1600–1850 cm−1.
The...