皮肤透导管方法对部分异常的肺静脉回归:一个案例系列
Omar Abdel-Razek1, Nhi Vo2, Jeffrey Weinstein2
1Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
The American journal of cardiology
|December 18, 2024
概括
穿皮关闭部分异常肺静脉回归 (PAPVR) 是成人患者的安全和可行的技术. 这种微创手术方法为那些不适合手术的人提供了一种新的选择,改善了血液动力学状况.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 部分异常肺静脉回归 (PAPVR) 是一种罕见的先天性心脏缺陷.
- 传统上通过手术纠正来管理,通常是在年轻时.
- 成年患者,特别是非手术候选人,治疗选择有限.
研究的目的:
- 为了证明成年人PAPVR的皮肤封闭的技术和安全性.
- 评估在不适合手术的患者中通过导管关闭的可行性.
- 评估穿皮关闭对血液动力学状态和心脏重塑的影响.
主要方法:
- 一系列病例描述了成人PAPVR患者异常肺静脉回归的皮肤封闭.
- 利用各种跨导管技术,有时结合起来,以实现闭塞.
- 专注于有干预迹象但没有手术选择的患者.
主要成果:
- 在3名成年患者中成功实现了穿皮关闭.
- 在手术后,患者的症状和血液动力学状况得到了明显改善.
- 在2名患者中观察到右心室大小的积极重塑.
结论:
- 皮肤穿透封闭PAPVR是一种可行的和安全的干预性心脏病学方法.
- 为患有PAPVR的成年患者,特别是非手术候选人提供了一种新的,最少的侵入性治疗选择.
- 过导管的关闭有效地解决了血液动力学后果,并可能导致心脏结构的改善.
相关概念视频
Ethics in Research
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
The Stanford Prison Experiment
The famous and controversial Stanford Prison Experiment, conducted by social psychologist Philip Zimbardo and his colleagues at Stanford University, demonstrated the power of social roles, social norms, and scripts.
Bullying
A modern form of aggression is bullying. As you learn in your study of child development, socializing and playing with other children is beneficial for children’s psychological development. However, as you may have experienced as a child, not all play behavior has positive outcomes. Some children are aggressive and want to play roughly. Other children are selfish and do not want to share toys. One form of negative social interactions among children that has become a national concern is bullying.
Sex Linked Disorders
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Conduct Disorder
Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...


