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Updated: Jun 4, 2025

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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核酸类似物和mopox:重新使用可重新使用的东西.

Ashleigh Shannon1, Bruno Canard1

  • 1Laboratoire Architecture et Fonction des Macromolécules Biologiques (AFMB), CNRS, Aix-Marseille Université, UMR7257, Marseille, France.

Antiviral research
|December 18, 2024
PubMed
概括

核类型的药物重用显示出对水 (mpox) 治疗的希望. 了解病毒聚合酶结构对于开发有效的抗病毒疗法来对抗mopox和其他感染至关重要.

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Biosynthesis of Nucleic Acids01:28

Biosynthesis of Nucleic Acids

Nucleic acid biosynthesis is a fundamental biochemical process that produces the purine and pyrimidine nucleotides essential for DNA and RNA synthesis. This pathway maintains a balanced nucleotide pool, preventing imbalances that could jeopardize genetic integrity and cellular function. Given the crucial role of nucleotides, their synthesis is tightly regulated to ensure proper cellular homeostasis.Purine BiosynthesisThe biosynthesis of purine nucleotides begins with ribose-5-phosphate, a...
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