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优化3D打印的体间设计. 第1部分:沉降的体外生物力学研究

S Harrison Farber¹, Alton J Oldham¹, Luke K O'Neill¹

¹Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.

The spine journal : official journal of the North American Spine Society

|December 18, 2024

概括

子沉降,体内融合的并发症,受到植入物表面积和地形的显著影响. 更高的骨密度也减少了沉降,强调了患者因素和植入物设计在预防这种并发症方面的重要性.

科学领域:

脊柱融合手术是指脊柱融合手术.
生物材料工程是生物材料的工程.
整形外科的植入物技术技术.

背景情况:

子沉降是体内融合的一个重要并发症,往往导致不良的临床结果.
3D打印的子提供了可定制的特性,如刚性和多孔性,但它们对沉降和聚变的影响尚未完全理解.

研究的目的:

调查3D打印体间格参数的修改如何影响体外骨模型 (第1部分) 中的沉降 (第1部分).
为了评估这些子参数在活体绵羊模型中对融合的生物学影响 (第二部分).

主要方法:

使用生物机械泡块模型与9种植入物类型,包括各种3D打印的子,PEEK子和固体子.
在两个不同密度的泡块中使用数字成像相关性测量了沉降度.
评估了表面积,多孔度,表面地形和材料特性对子沉降和刚性的影响.

主要成果:

增加植入物表面积显著减少沉降 (p≤.01).
多孔表面地形增加了沉降,而无孔表面减少了沉降 (p<.001).
植入物孔隙性和材料特性没有显著影响沉降 (分别为p≥.35和p≥.19).
更高的泡密度导致沉降率显著降低 (p<.001).

结论:

植入物表面积和地形是影响体间沉降的关键因素.
子的刚性,孔隙性和材料特性在体外模型中没有影响沉降.
骨密度是预防沉降的关键因素,在手术期间强调患者优化和端板保护.

关键词:

通过3D打印的3D打印.生物力学生物力学身体间的融合是身体间的融合.模块模块是一个模块.皮克皮克 (Peek) 是一种古老的风格.聚乙基 (Polyetheretherketone) 是一种聚乙基.多孔性多孔性的骨头是看到了.硬性这是一种硬性.在此之前,我一直在研究Subsidence.表面的地形图形是表面的地形.的是什么? 的是什么?

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