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相关概念视频

Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

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Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
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Schizophrenia01:17

Schizophrenia

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Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
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Prosopagnosia01:24

Prosopagnosia

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Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
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Visual Agnosia01:12

Visual Agnosia

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Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
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Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

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Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
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The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
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Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
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在精神病中受损的边界对象感知.

Rohit S Kamath1, Kimberly B Weldon2, Hannah R Moser1

  • 1Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, Minnesota.

Biological psychiatry. Cognitive neuroscience and neuroimaging
|December 18, 2024
PubMed
概括

对视觉感知至关重要的轮整合在患有精神病精神病理 (PwPP) 的人群中受损. 这种缺陷在精神分裂症中尤为明显,与异常的大脑连接和认知功能障碍有关.

关键词:
生物学上的亲属.双极性障碍是一种双极性障碍.轮整合 轮整合 轮整合功能性核磁共振成像 (MRI) 是一种功能性核磁共振成像.功能连接性的功能连接性.精神分裂症是一种精神分裂症.视觉感知 视觉感知 视觉感知

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科学领域:

  • 神经科学是一个神经科学.
  • 认知心理学 认知心理学
  • 精神病学是一个精神病学.

背景情况:

  • 轮整合,即从不同的元素中感知统一线条的能力,已知在精神分裂症中受损.
  • 新出现的证据表明,这种缺陷可能与更广泛的精神病症状有关,而不是仅仅是精神分裂症.

研究的目的:

  • 在患有精神病精神病理的个体的跨诊断样本中调查轮整合缺陷.
  • 使用超高场功能磁共振成像 (fMRI) 探索这些缺陷的神经基础.

主要方法:

  • 用一种心理物理行为任务来量化轮感知.
  • 7T fMRI用于在类似的轮感知任务中测量大脑活动和功能连接.
  • 参与者包括患有精神病精神病理 (PwPP) 的个人,健康的对照者和生物亲属.

主要成果:

  • 与对照组和亲属相比,患有精神病精神病理 (PwPP) 的人表现出受损的轮歧视.
  • 精神分裂症患者的表现比双相情感障碍患者差.
  • 在PwPP中,fMRI揭示了侧向尾皮层反应的增加和异常的视觉大脑连接,特别是在区分目标和分心器时.

结论:

  • 这些发现支持精神病性精神病理学,特别是精神分裂症中受损的轮整合.
  • 这种缺陷与认知功能障碍有关,可能源于视觉处理区域的异常功能连接.
  • 如果无法抑制背景噪声,可能会导致PwPP的轮处理受损.