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Updated: Jun 4, 2025

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在瘤学中,对剂量检测研究设计的概率视角

Zhiwei Zhang1

  • 1Biostatistics Innovation Group, Gilead Sciences, Foster City, California, USA.

Pharmaceutical statistics
|December 18, 2024
PubMed
概括

本研究引入了概括概率比 (GLR) 来评估瘤学临床试验中剂量转换决策的统计证据. 基于GLR的设计提供了一个统一的框架来比较方法并改善最大耐受剂量 (MTD) 估计.

关键词:
降低剂量升级的剂量升级.剂量升级剂量的升级.选择剂量选择剂量选择剂量过渡 剂量过渡概率定律是概率的一般定律.同位素回归的同位素回归单调性是一种单调性.第1阶段试验设计试验

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