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相关概念视频

Threats to Biodiversity01:50

Threats to Biodiversity

There have been five major extinction events throughout geological history, resulting in the elimination of biodiversity, followed by a rebound of species that adapted to the new conditions. In the current geological epoch, the Holocene, there is a sixth extinction event in progress. This mass extinction has been attributed to human activities and is thus provisionally called the Anthropocene. In 2019 the human population reached 7.7 billion people and is projected to comprise 10 billion by...
Predator-Prey Interactions02:39

Predator-Prey Interactions

Predators consume prey for energy. Predators that acquire prey and prey that avoid predation both increase their chances of survival and reproduction (i.e., fitness). Routine predator-prey interactions elicit mutual adaptations that improve predator offenses, such as claws, teeth, and speed, as well as prey defenses, including crypsis, aposematism, and mimicry. Thus, predator-prey interactions resemble an evolutionary arms race.Although predation is commonly associated with carnivory, for...
Oxidative Cleavage of Alkenes: Ozonolysis01:46

Oxidative Cleavage of Alkenes: Ozonolysis

In ozonolysis, ozone is used to cleave a carbon–carbon double bond to form aldehydes and ketones, or carboxylic acids, depending on the work-up.
Ozone is a symmetrical bent molecule stabilized by a resonance structure.
Oxidation and Reduction of Organic Molecules01:19

Oxidation and Reduction of Organic Molecules

Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, which occur at the same time. An oxidation reaction strips an electron from an atom in a compound, and the addition of this electron to another compound is a reduction reaction. Because oxidation and reduction usually occur together, these pairs of reactions are called redox reactions.
The removal of an electron from a molecule, results in a...
Instinct Theory01:29

Instinct Theory

Instinct theory proposes that innate biological instincts, like animal behavioral patterns, primarily drive human behavior. These instincts are inborn, not learned, and are fundamental to decision-making and action. Just as animals rely on instincts for critical survival functions such as migration, nest building, and defense, humans are also believed to exhibit behaviors rooted in evolutionary needs. For example, the instinct to reproduce motivates sexual behavior, while territorial instincts...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...

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The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
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米诺环素诱导的狼

Shinya Hasegawa1, Steven M Craig2, Hiroyuki Suzuki3

  • 1Division of Infectious Diseases, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA shinya-hasegawa@uiowa.edu.

BMJ case reports
|December 18, 2024
PubMed
概括

长期使用抗生素治疗一般性可能会造成伤害,如药物诱导的狼. 抗生素管理和药物审查可以防止非传染性皮肤疾病的不适当处方.

科学领域:

  • 皮肤病学 皮肤病学
  • 药理学 药理学是指药理学的学科.
  • 传染性疾病 传染性疾病

背景情况:

  • 抗生素经常被处方用于非传染性皮肤病,如,通常是长时间的.
  • 不适当使用抗生素会导致抗菌素耐药性,药物不良反应和医疗保健成本增加.

研究的目的:

  • 突出长期使用抗生素在非传染性皮肤病的风险.
  • 为了呈现一种药物诱导的狼病例,该病例是针对的长期米诺环林治疗的次要病例.
  • 倡导改善抗生素管理和降低处方策略.

主要方法:

  • 一个青少年晚期患有的病例报告,用米诺环林治疗了两年多.
  • 对临床结果的审查,包括药物诱导狼的发展.
  • 讨论潜在的干预措施,如抗生素管理和以患者为中心的药物评价.

主要成果:

  • 患者患有药物诱导的狼,这归因于长期使用米诺环素.
  • 这导致了多次医疗保健访问,广泛的检查和大量成本.
  • 该案例说明了不适当的抗生素治疗可能导致严重不良事件的可能性.

结论:

关键词:
这是一种自身免疫力.皮肤病学 皮肤病学传染性疾病 传染性疾病

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  • 对非传染性皮肤病的不适当,长时间的抗生素处方会带来重大风险.
  • 合作努力,包括抗生素管理和个性化处方,对于减轻这些风险至关重要.
  • 以患者为中心的药物评价对于优化治疗和预防危害至关重要.