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使用数字PCR研究KRAS变异在垂体瘤中的流行率

Veronica Aran1,2, Elisa Lamback3,4,5, Renan Lyra Miranda4

  • 1Laboratório de Biomedicina do Cérebro, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil.

Journal of neuroendocrinology
|December 18, 2024
PubMed
概括

下垂体瘤可以携带KRAS突变,这是以前由于技术限制而未被发现的发现. 这一发现为瘤发育提供了新的见解,并为垂体腺瘤提供了潜在的治疗策略.

关键词:
克拉斯 (Kras) 是一个国家.克拉斯变种的KRAS变种数字PCR是数字的PCR.pituitary 瘤 pituitary 瘤 pituitary 瘤 瘤 瘤 瘤

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The Ras Gene02:38

The Ras Gene

The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a...
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