无症状侵蚀性食道炎 无症状侵蚀性食道炎
Yixuan Du1, Ashley Spencer1, Pabitra Roy1
1Penn State College of Medicine, Hershey, PA, USA.
Digestive diseases and sciences
|December 18, 2024
概括
无症状侵蚀性食道炎 (AEE) 涉及食道损伤,没有典型的GERD症状. 需要进一步的研究来了解AEE的原因,并改善患者的治疗,防止严重的并发症.
科学领域:
- 胃肠病学 胃肠病学
- 食道疾病 食道疾病
- 消化系统健康 消化系统健康
背景情况:
- 胃食道逆流性疾病 (GERD) 通常会导致胃酸逆流引起的烧和疼痛等症状.
- 食道粘膜损伤,典型的GERD,可以在没有症状的情况下发生,这种情况被称为无症状侵蚀性食道炎 (AEE).
- 由于诊断延迟和潜在的并发症,如狭窄和癌症,AEE给公共卫生带来了挑战.
研究的目的:
- 综合审查关于无症状侵蚀性食道炎 (AEE) 的科学文献.
- 检查AEE的患病率,临床特征和潜在原因.
- 确定用于更好地描述和管理AEE的战略.
主要方法:
- 对AEE现有的科学文献进行系统审查.
- 对专注于无同时出现GERD症状的食道粘膜损伤的研究进行分析.
- 检查有关AEE流行,临床表现和促成因素的数据.
主要成果:
- 在没有典型的GERD症状的情况下,AEE的特点是食道损伤的内镜证据 (侵蚀,,巴雷特食道).
- 对AEE的确切原因和患病率尚不清楚,这阻碍了最终的管理准则.
- 患有AEE的患者可能长时间未被诊断,从而增加并发症的风险.
结论:
- 在GERD频谱中,AEE代表了一个重要的,研究不足的条件.
- 进一步的研究对于了解AEE病因和开发有效的诊断和管理策略至关重要.
- 改善AEE的特征是减轻受影响个体的长期健康风险的关键.
相关概念视频
Barrett Esophagus-II: Clinical Manifestations and Management
103
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
103
Barrett Esophagus-I: Introduction
64
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
64
Gastroesophageal Reflux Disease II: Clinical Features and Management
54
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
54
Esophageal Strictures-I: Introduction
65
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
65
Esophageal Strictures-II: Clinical Features and Management
46
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
46
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
283
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
283


