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对于放射后复发的食道状细胞癌的内镜下粘膜剖析

Yasuhiro Inokuchi¹, Kyoko Furusawa², Kei Hayashi³

¹Department of Gastroenterology, Yokohama Minami Kyosai Hospital, 1-21-1 Kanazawa-Ku, Mutsuura Higashi, Yokohama, Kanagawa, 236-0037, Japan. y-inokuchi@minamikyousai.jp.

Digestive diseases and sciences

|December 18, 2024

概括

在被辐射的场内对食道癌的救生内镜下粘膜切割 (ESD) 是可行的,可以实现高切割率. 仔细的随访至关重要,以监测其他恶性瘤,并预防诸如吸血等并发症.

科学领域:

胃肠病学和内镜检查
在瘤学瘤学.
辐射瘤学辐射瘤学

背景情况:

在先前照射过的领域内,对于食道状细胞癌 (ESCC) 的救援内镜下粘膜剖析 (ESD) 的可行性和结果尚不清楚.
在被照射区域中评估元慢性ESCC的ESD对于治疗规划至关重要.

研究的目的:

评估ESD对ESCC在辐射场中的可行性.
确定影响ESD成功的因素,并评估患者的预后.
在这种情况下,确定ESD后的最佳后续策略.

主要方法:

在照射场内对30名患有41个ESCC病变的患者进行了回顾性分析,这些患者接受了救援ESD或ESD治疗.
评估患者和病变特征,短期和长期结果.
从2013年1月到2023年12月在Kanagawa癌症中心收集的数据.

主要成果:

实现了高的块状解剖率:91.3%的救援ESD和100%的元时代ESD.
在超慢性ESD病例中,不良事件包括吸入性肺炎 (12.5%) 和术后狭窄 (12.5%);在救援ESD中没有不良事件.
用救援ESD治疗的病变没有复发. 五年整体生存率为74.9%,没有人死于食道癌.

结论:

在被辐射的场地中,ESCC可以进行救援和超慢性ESD,提供高块切割率和有效的局部控制.
对其他器官恶性瘤的ESD后监测至关重要.
渴望预防策略可以提高患者的预后.

关键词:

内镜切除术是一种内镜切除术.内镜下粘膜切割进行内镜下粘膜切割.食管状细胞癌的癌症甲基时代的甲基时代的辐射辐射辐射辐射辐射辐射辐射在救援中,救援者.

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