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Updated: Jun 4, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
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使用AFM和深度神经网络确定RNA对应物的结构

Maximilia F S Degenhardt1, Hermann F Degenhardt1, Yuba R Bhandari1

  • 1Protein-Nucleic Acid Interaction Section, Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.

Nature
|December 18, 2024
PubMed
概括

确定复杂的RNA结构是一个挑战. 一种名为HORNET的新方法使用原子力显微镜和机器学习来揭示灵活的RNA分子的3D形状,进步RNA结构生物学.

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