使用集群分析类型学的回归的稳定性评估:一个启动程序,在状态序列分析中应用
Leonard Roth1, Matthias Studer2, Emilie Zuercher3
1Department of Epidemiology and Health Systems, Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Route de La Corniche 10, 1010, Lausanne, Switzerland. leonard.roth@unisante.ch.
BMC medical research methodology
|December 18, 2024
概括
通过忽视采样不确定性,标准序列分析可能会产生错误的结论. 本研究引入了一种可靠的方法来评估回归结果,确保在轨迹模式分析中获得可靠的结果.
科学领域:
- 社会科学 社会科学 社会科学
- 生物医学数据科学 生物医学数据科学
背景情况:
- 标准序列分析集群轨迹,但往往忽视采样不确定性.
- 这种监督可能导致回归模型中不准确的结论,将模式与共变量联系起来.
研究的目的:
- 引入一种新的程序来评估序列分析中的回归结果的稳定性.
- 为了考虑轨迹类型和相关回归的采样不确定性.
主要方法:
- 使用引导样本来构建新的类型学和估计回归模型.
- 采用多级建模框架,模仿元分析,以结合引导估计.
- 将该方法应用于瑞士糖尿病患者队列中的医疗保健利用轨迹.
主要成果:
- 该程序产生了可靠的估计和95%的预测间隔,考虑到采样不确定性.
- 在集群中确定了中心和边界轨迹.
- 在示例申请中,脂质检测和医疗保健利用之间的关联没有在稳定性评估上得到支持.
结论:
- 使用集群分析类型学 (RARCAT) 开发的回归的稳定性评估提高了关联研究的可靠性.
- RARCAT适用于任何结合聚类与回归的分析,超越状态序列分析.
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