怀孕期间的妊娠体重增加是Omicron感染的危险因素:一项回顾性病例控制研究
Lin Yao1, Peizhen Zhang1, Jin Zhou1
1Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Sun Yat-Sen University, 600#Tian He Road, Guangzhou, P. R. China.
BMC pregnancy and childbirth
|December 18, 2024
概括
在正常体重的孕妇中,过度的妊娠体重增加增加了Omicron感染的风险. 这一发现凸显了监测GWG的重要性,以便在疫情期间获得更好的妊娠结果.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 孕期体重增加 (GWG) 与孕妇感染Omicron感染风险之间的关系尚未得到充分证实.
- 了解这种关联对于COVID-19大流行期间的孕产妇健康至关重要.
研究的目的:
- 为了确定怀孕期间GWG是否与较高的Omicron感染风险有关.
- 为了确定孕妇感染Omicron的潜在风险因素.
主要方法:
- 对369名孕妇进行了回顾性病例控制研究.
- 数据是从孙中山大学第三附属医院在2022年12月1日至31日期间收集的.
- 统计分析包括千二测试,t测试/ANOVA和多变量逻辑回归.
主要成果:
- 超过医学研究所 (IOM) 准则的GWG孕妇显示,Omicron感染的风险显著增加 (P=0.006).
- 经过对混因素进行调整 (OR=2.55,P=0.004) 后,这种关联仍然显著.
- 在正常体重的女性中,GWG高于IOM是一个独立的Omicron感染风险因素 (OR=2.56,P=0.01).
结论:
- 超过IOM建议的孕期体重增加是正常体重孕妇感染Omicron的独立风险因素.
- 这表明,GWG管理可能在减轻怀孕期间感染风险方面发挥作用.
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