协议:美国妇女:从流行病学上评估风险 (AWARE) 队列研究
Rebecca Schnall1,2,3, Mirjam-Colette Kempf4,5,6, Gregory Phillips7
1School of Nursing, Columbia University, New York, NY, 10032, USA. rb897@columbia.edu.
BMC public health
|December 18, 2024
概括
采用创新的招聘策略,将1800名多元化的女性纳入全国性研究,以了解艾滋病毒风险因素. 这项研究旨在减少艾滋病毒的发病率,并改善妇女的预防.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 社会和行为科学 社会和行为科学
背景情况:
- 尽管取得了进展,但Cisgender女性的艾滋病毒发病率仍然是一个重大的公共卫生问题,不足以实现疫情控制目标.
- 关键人群,包括 cisgender 女性,需要有针对性的策略来减少艾滋病毒的传播和改善健康结果.
研究的目的:
- 招募和保留一个庞大,多样化的全国样本 (N=1800),包括14岁以上的艾滋病毒血清转换风险较高的 cisgender 女性.
- 使用社会生态框架调查与艾滋病毒相关的性风险和艾滋病毒发病率的预测因素.
- 采用创新的电子招聘方法,包括以社区为基础的广告的社交媒体.
主要方法:
- 一项基于美国的全国纵向队列研究,涉及艾滋病毒血清转换的可能性更高的Cisgender女性.
- 通过调查收集人口统计数据,物质使用,心理健康症状,人际暴力和社会因素.
- 采集生物样本 (阴道/直肠抽样,血液) 每6个月,持续2年,检测艾滋病毒和其他性传播感染.
主要成果:
- 参与者招聘于2023年6月开始.
- 预计基线招生将在2025年7月结束.
结论:
- 文化敏感和创新的策略对于提高艾滋病毒预防和治疗的机会至关重要.
- 研究结果将指导未来的研究,干预开发和公共政策,以打击这一群体的艾滋病毒流行病.
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