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相对较低的BMI调整的小腿周长与非肥胖成年人的代谢不健康的表型有关:一个横截面研究
Xiaotong Wang1, Na Ta2, Shan Hu3
1Department of Chronic Non-communication Disease Control and Prevention, Tianjin Xiqing District Center for Disease Control and Prevention, Tianjin, China.
BMC public health
|December 19, 2024
概括
代谢不健康的非肥胖个体面临更高的心血管风险. 监测体重指数调整的小牛周长 (BMI调整的CC) 可以帮助识别和减轻非肥胖人群中的这些风险.
科学领域:
- 心血管健康 心血管健康
- 代谢健康 代谢健康
- 营养科学 营养科学
背景情况:
- 代谢不健康的非肥胖 (MUNO) 个体患心血管疾病的风险增加.
- 这一群人群往往没有得到足够的临床关注.
- 了解MUNO个体的风险因素对于公共卫生至关重要.
研究的目的:
- 调查身体质量指数调整的小牛周长 (BMI调整的CC) 和代谢不健康的非肥胖 (MUNO) 状态之间的关联.
- 分析这一关联在美国非肥胖成年人的代表性样本中.
主要方法:
- 利用来自NHANES数据库的9,628名美国非肥胖成年人的数据.
- 通过≥2组分的代谢异常来定义代谢不健康.
- 使用加权多重逻辑回归和斯皮尔曼相关性来分析BMI调整后的CC,BMI调整后的骨肌肉质量 (SMM) 和MUNO.
主要成果:
- 较高的BMI调整后的CC和BMI调整后的SMM四分位数与较低的MUNO几率 (ORs <0.4) 有显著的关联.
- 经BMI调整的CC显示与经BMI调整的SMM (r=0.48) 有正相关性.
- 在BMI调整后的CC和MUNO之间发现了微弱的非线性关联.
结论:
- 根据BMI调整的CC与代谢不健康的非肥胖状态相反相关.
- 监测BMI调整的CC可能是公共卫生的一个有价值的策略,以减少疾病负担,特别是在非肥胖个体.
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