药剂师为血管外科手术患者主导的干预:关于减少与药物有关的问题的前性研究
Slavka Porubcova1,2, Kristina Szmicsekova1,3, Kristina Lajtmanova1
1Hospital Pharmacy, The National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
药剂师的干预显著减少了血管外科手术患者的药物相关问题. 这项研究强调了药剂师在改善住院期间患者安全和药物管理方面的重要性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 血管外科 血管外科
背景情况:
- 血管外科手术患者面临多药和药物相关问题的高风险.
- 关于医院药剂师在多学科血管外科手术团队中的影响的研究有限.
- 一项临床研究 (NCT04930302) 评估了药剂师的干预措施,以减少住院血管手术患者的药物相关问题.
研究的目的:
- 评估药剂师主导干预措施在血管外科手术患者中减少与药物相关问题的有效性.
- 在这个患者群体中分析DRP的类型和原因.
- 评估患者对干预后药物治疗的理解.
主要方法:
- 在斯洛伐克进行了一项为期一年的研究,涉及105名患有动脉或下肢动脉疾病的成年患者,他们服用≥3种药物.
- 医院药剂师在入院和出院时进行药物调和和审查.
- 药剂师的干预被记录下来,与医生沟通,患者接受出院教育.
主要成果:
- 平均DRP数量从入院时的2.3±2.1显著下降到出院时的1.6±1.8 (p < 0.001).
- 心血管类药物最常涉及 (41.9%).
- 未经治疗的适应症,特别是未能为下肢动脉疾病处方他类药物,是常见的 (40.3%). 药剂师干预的接受率在入院时为66.1%.
结论:
- 药剂师主导的干预措施显然可以减少住院血管外科手术患者的药物相关问题.
- 这些干预措施提高了患者的安全性,并为临床结果做出了积极贡献.
- 超过50%的参与者观察到患者对药物治疗的理解得到了改善.
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