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Updated: Jun 4, 2025

Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice
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肝功能障碍:对帕克利塔塞尔毒性,剂量修改和整体存活时间的影响

Marieke Schmidt1, Robin Vernooij2,3,4, Merel van Nuland1

  • 1Department of Clinical Pharmacy, University Medical Center Utrecht, PO Box 85500, Utrecht, 3508 GA, The Netherlands.

BMC cancer
|December 19, 2024
PubMed
概括

肝功能受损会增加严重血液毒性的风险,并降低治疗晚期乳腺癌,卵巢癌或食道癌的帕克利塔塞尔患者的整体存活率 (OS). 剂量修改应仔细考虑.

关键词:
肝功能受损 肝功能受损帕克利塔塞尔毒性的毒性帕克利塔塞尔剂量修改

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