西藏青少年高海拔结核病的临床特征:一项回顾性研究
Min Shen1, Wen Luo1, Banjiu Luobu2
1Department of Respiratory Medicine, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong Province, 518112, China.
BMC pulmonary medicine
|December 19, 2024
概括
在高海拔地区的青少年肺结核 (TB) 通常呈现为亚临床结核病,症状比成年人少. 在青少年中早期诊断这种高海拔结核病需要考虑先前的暴露,并使用像GeneXpert和ESR这样的测试.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 儿科 儿科 儿科
背景情况:
- 在高海拔地区,青少年肺结核 (TB) 缺乏认可.
- 这项研究侧重于中国高海拔地区青少年肺结核的独特临床特征.
研究的目的:
- 研究居住在高海拔地区的青少年肺结核患者的临床特征.
- 将这些特征与同一个环境中的成年肺结核患者进行比较.
主要方法:
- 在林人民医院对新诊断的肺结核患者的回顾性分析.
- 收集人口统计,临床,实验室和成像数据.
- 在唾液样本上使用GeneXpert MTB/RIF测定检测Mycobacterium结核病.
主要成果:
- 青少年 (n=63) 比成年人 (n=192) 显示出较少的典型结核病症状.
- 与成年人 (8.3%) 相比,青少年 (23.8%) 的亚临床结核病发病率更高.
- 青少年的结核病暴露率较高 (38.8%),红细胞沉率 (ESR) 高.
结论:
- 在高海拔地区的青少年肺结核经常是亚临床的,并且与更高的先前结核病暴露有关.
- 在这种人群中,GeneXpert测试和ESR对于诊断亚临床肺结核至关重要.
相关概念视频
Pulmonary Tuberculosis I
220
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
220
Pulmonary Tuberculosis III
303
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
303
Pulmonary Tuberculosis IV
133
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
133
Pulmonary Tuberculosis II
211
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
211
Pulmonary Tuberculosis V
170
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
170
Other Pulmonary Disorders
803
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
803


