患有心房动的患者的咖啡消费和不良心血管事件
Vasco Iten1,2, Elena Herber1,2, Michael Coslovsky1,2,3
1Cardiovascular Research Institute Basel, University Hospital Basel, University of Basel, Basel, Switzerland.
BMC medicine
|December 19, 2024
概括
每天喝咖啡可能会减少心脏动 (AF) 患者的主要心血管事件 (MACE). 适度摄入量 (2-3杯) 显示风险最低,这表明咖啡对AF结果并不不利.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 一般人群研究表明,适度饮用咖啡可以降低主要心血管事件 (MACE) 发生率.
- 对于心房动 (AF) 患者的咖啡消费安全性存在担忧.
研究的目的:
- 为了研究每日咖啡消费和MACE在被诊断为AF的患者之间的关联.
主要方法:
- 分析了来自两个大型前性观察多中心队列研究 (Swiss-AF和Beat-AF) 的数据.
- 咖啡消费分为"日常"和"非日常".
- 用于评估MACE风险的时间更新的多变量调整的考克斯回归分析.
主要成果:
- 与非每日饮用相比,每日饮用咖啡与MACE的危险性降低了23%.
- 适度咖啡摄入量 (每天2-3杯) 显示出MACE危险比率最低.
- 每日MACE的发病率为5.09/100人年,而非每日消费者为7.49/100人年.
结论:
- 每日咖啡消费与MACE减少,急性心力衰竭住院和AF患者全因死亡率有关.
- 在每日咖啡摄入量和AF患者的不良结果之间没有发现不利的关联.
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