抑制控制训练对失眠的好处,睡眠时间短的表型:一个试点随机试验
Haobo Zhang1,2, Zhangwei Lv1,2, Hanfei Chen1,2
1Sleep and NeuroImaging Center, Faculty of Psychology, Southwest University, Chongqing, 400715, China.
BMC medicine
|December 19, 2024
概括
睡眠时间短暂的失眠障碍 (ISSD) 显示出受损的反应抑制,与正常睡眠时间失眠 (INSD) 不同. 响应抑制训练通过改善睡眠质量和减少失眠严重程度,有利于ISSD.
科学领域:
- 神经科学是一个神经科学.
- 睡眠医学 睡眠医学
- 认知心理学 认知心理学
背景情况:
- 失眠障碍 (ID) 有两个表型:短睡眠时间 (ISSD) 和正常睡眠时间 (INSD).
- ISSD可能涉及皮层抑制功能受损,这是其患病率的潜在驱动因素.
- 本研究研究了ID表型和训练效应之间的响应抑制差异.
研究的目的:
- 为了比较ISSD和INSD的响应抑制.
- 评估响应抑制训练对两种ID表型的睡眠质量和严重性的疗效.
- 探索不同失眠表型的潜在机制.
主要方法:
- 招募了22名健康对照 (HC) 和81名ID患者 (分为ISSD和INSD).
- 评估睡眠特征 (多睡眠学),临床测量 (PSQI,ISI,PSAS) 和Go/NoGo任务执行.
- 给ISSD和INSD的子组进行了3周的适应反应抑制训练.
主要成果:
- ISSD患者的睡眠延迟时间比HC更长;清醒和轻度睡眠时间比INSD更短.
- 在ISSD培训组中,响应抑制训练显著降低了PSQI和ISI分数.
- 在INSD的训练和对照组都在PSQI,ISI和干预后的认知兴奋中表现出改善.
结论:
- 阻断反应受损的特征是ISSD,这表明皮质抑制功能障碍.
- 似乎INSD的发病与认知情感兴奋有关.
- 响应抑制训练提供了一个有针对性的干预措施,以缓解ISSD的睡眠问题.
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