无症状的多焦点无血管亡,这是一个常被忽视的发现,在患有系统性红血狼的患者
Forough Nadi1, Esmat Abdollahpour2, Babak Fallahi3
1Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
BMC rheumatology
|December 19, 2024
概括
近一半的系统性红斑狼 (SLE) 患者患有症状性骨髓缩也患有无症状的骨髓缩. 使用SPECT骨光学和MRI的早期检测对于预防关节损伤至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
背景情况:
- 骨髓缩是系统性红斑狼 (SLE) 患者的衰弱并发症,经常呈现无症状.
- 早期发现和治疗无症状骨髓缩是防止关节破坏的关键.
研究的目的:
- 评估SLE患者无症状骨髓缩的患病率,诊断出有症状的骨髓缩.
- 检查与无症状骨质死结的发展相关的风险因素.
主要方法:
- 一项涉及SLE患者最近出现症状骨髓缩的横截面研究.
- 使用三相SPECT骨光学扫描来选无症状骨硬化,用MRI进行确认.
- 评估了无症状骨髓缩的患病率,关节参与,位置和危险因素.
主要成果:
- 47%的患有症状性骨髓缩症的患者 (占17例中的8例) 也患有无症状性骨髓缩症.
- 左膝盖是最常见的无症状关节 (25%),而左部是最常见的症状关节 (23.07%).
- 较高的疾病发病年龄与无症状骨髓缩明显相关 (p=0.046).
结论:
- 在SLE患者中无症状骨髓缩的高发病率与疾病特征和皮质类固醇使用有关.
- 全身SPECT骨光学扫描和MRI对于早期检测无症状骨硬化是必不可少的.
- 需要及时干预,以防止SLE患者的失能关节损伤.
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