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Updated: Jun 4, 2025

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
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HIPSD&R-seq能够实现可扩展的基因组拷贝数和转录组分析

Jan Otoničar1,2,3, Olga Lazareva4,5,6, Jan-Philipp Mallm7,8

  • 1Group Genome Instability in Tumors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Genome biology
|December 19, 2024
PubMed
概括

我们开发了HIPSD&R-seq,这是一种用于高通量单细胞DNA和RNA测序的可扩展测试. 这种方法有效地检测罕见的癌症克隆,同时分析成千上万的细胞.

关键词:
单细胞 DNA 测序单细胞副本 编号 配置文件一个单细胞多组体.

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RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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