膀本身是否可以"测量"体积,从而帮助确定何时应该开始排尿? 在ICI-RS 2024中,
Gommert Van Koeveringe1, Karen D McCloskey2, Anthony J Kanai3
1Department of Urology, Research Institute for Mental Health and Neuroscience, Maastricht University and Maastricht University Medical Center+ (MUMC+), Maastricht, The Netherlands.
Neurourology and urodynamics
|December 19, 2024
概括
膀壁含有感知拉伸和化学信号的机制,影响排泄的启动. 膀的形状和透性也调节了中枢神经系统的信号,影响了空气发生时.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 神经科学是一个神经科学.
- 细胞生物学 细胞生物学
背景情况:
- 膀控制排泄的确切机制是复杂的,并未完全理解.
- 了解膀的感觉机制对于管理膀功能障碍和失禁至关重要.
研究的目的:
- 为了研究膀控制或调节排泄过程的开始的内在能力.
主要方法:
- 讨论和提议会议在国际商失禁研究协会 (ICI-RS) 2024年会议.
- 审查最近关于膀壁传感,信号传导和尿液储存调节的研究.
主要成果:
- 膀壁细胞具有感知当地环境的离子通道和受体,有助于运动感官通路.
- 纯能系统促进了从膀伸展到 afferent 信号的化学敏感转导.
- 泌尿器的阿基尼酸压缩素生产调节水素道,减少膀体积,延迟充满感觉.
- 膀的形状影响体积感知,可能与膀过度活跃有关.
结论:
- 膀传感体积,信号值,形状和透性的机制影响到中枢神经系统 (CNS) 的信号的时间和性质.
- 膀衍生的信号的等级分级,与其他身体和中央信号一起,决定了排泄的开始.
相关概念视频
01:23Urinary Bladder
386
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
386
01:23Renal Clearance
718
The glomerular filtration rate (GFR) is a critical marker of kidney function, reflecting the efficiency of filtration by the glomeruli. Renal clearance of specific substances, such as inulin or creatinine, is commonly used to measure GFR.
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
718