在糖尿病下肢截肢患者中,手术前的血红蛋白水平和贫血频率
Kaissar Yammine1,2,3, Ghadi Abou Orm1, Mohamad Omar Honeine1
1Department of Orthopedic Surgery, Lebanese American University Medical Center-Rizk Hospital, Lebanese American University, School of Medicine, Beirut, Lebanon.
Vascular
|December 19, 2024
概括
糖尿病下肢截肢 (LEAs) 显示出高贫血患病率 (90.3%). 术前贫血可能会增加术后风险,需要进一步调查和潜在的干预措施.
科学领域:
- 内分泌学 在内分泌学.
- 血液学 血液学 血液学
- 血管外科 血管外科
背景情况:
- 贫血在糖尿病足中很常见,但在接受下肢截肢 (LEAs) 的患者中没有研究过.
- 在这个高危人群中,手术前的贫血可能会加剧术后的发病率和死亡率.
- 存在关于手术前血红蛋白 (Hg) 水平和糖尿病LEA患者贫血患病率的知识差距.
研究的目的:
- 为了确定糖尿病LEA入院患者中贫血的患病率.
- 在这个患者群体中评估手术前血红蛋白 (Hg) 水平.
- 探索Hg水平与手术前特征之间的关系.
主要方法:
- 横截面研究设计. 截面研究设计.
- 主要结局:手术前平均Hg水平和贫血频率.
- 二级结局:Hg水平与血清肌素之间的相关性.
主要成果:
- 分析了来自141名患者的192例LEA病例;90.3%是贫血.
- 平均Hg为10.6±1.8g/dL,轻度,中度和重度贫血分别发生在46.8%,40.8%和4.3%的病例中.
- 在血清肌素和Hg水平之间发现了显著的负相关性 (p = .037).
结论:
- 大多数接受糖尿病LEA的患者是贫血的.
- 贫血可能会对肢体输液产生负面影响,并增加术后死亡率.
- 建议对手术前输血干预措施进行进一步的研究.
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