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杜洛特格拉维尔药理动学的遗传变异以及与安全性和疗效结果的关系:系统性审查

Lisanne A H Bevers1, Rebecca L Jensen2, Andrew Owen2

  • 1Department of Pharmacy, Radboudumc Research Institute for medical Innovation (RIMI), Radboud University Medical Center, Nijmegen, The Netherlands.

Pharmacogenomics
|December 19, 2024
PubMed
概括

对多卢特格拉维尔 (DTG) 的药物基因组学 (PGx) 研究表明,遗传变异会影响药物暴露和潜在的副作用. 虽然PGx测试可能有助于理解,但目前的证据不支持其用于DTG治疗的常规临床使用.

关键词:
多卢特格拉维尔 (Dolutegravir) 是一种药物.艾滋病病毒 艾滋病病毒 艾滋病病毒抗逆转录病毒药物使用药理动力学是药理动力学的一个方面.药物基因组学 药物基因组学药物动力学 药物动力学

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