瑞典埃索诺菲尔性食管炎的流行病学 - 全国范围的基于人口的研究
Aldona Dlugosz1, Anders Berglund2, Milica Uhde3
1H7 Department of Medicine, Huddinge, Karolinska institutet, Stockholm, Sweden.
Scandinavian journal of gastroenterology
|December 19, 2024
概括
从2012年到2021年,埃索诺菲尔性食道炎 (EoE) 的发病率和流行率在瑞典显著增加. 在瑞典各地观察到EoE患病率的区域差异,需要进一步调查.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 生性食道炎 (EoE) 是一种慢性食道炎症疾病,在全球范围内发病率不断增加.
- 之前的研究表明,近几十年来,EoE诊断的数量大幅增加.
研究的目的:
- 确定瑞典EoE的发病率和流行趋势.
- 分析瑞典境内EoE患病率的地理差异.
主要方法:
- 利用全国范围的基于人口的注册表,包括国家患者注册表.
- 在2011年至2021年期间,使用ICD-10-SE代码K20.9A用于住院 (住院和门诊) 的确定的EoE病例.
- 计算每10万人/年发生率和每10万人/年流行率.
主要成果:
- 2011年没有记录EoE医院访问;在2012-2021年期间,确定了3,243名事件患者.
- 发病率从每10万人/年 (2012-2021) 的1.59上升到5.34.
- 患病率从每10万人1.29增加到每10万人31.02 (2012-2021),在2021年发现了显著的区域差异.
结论:
- 在瑞典,EoE的发病率和流行率随着时间的推移显著增加.
- 在瑞典,EoE患病率存在实质性的地理差异.
- 需要进一步的研究来了解这些区域差异背后的原因.
相关概念视频
Esophageal Strictures-I: Introduction
65
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
65
Barrett Esophagus-I: Introduction
64
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
64
Barrett Esophagus-II: Clinical Manifestations and Management
103
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
103
Gastroesophageal Reflux Disease II: Clinical Features and Management
54
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
54


