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Updated: Jun 17, 2026

Micro-particle Image Velocimetry for Velocity Profile Measurements of Micro Blood Flows

Published on: April 25, 2013

以光导向的动态幻影来模仿生物医学应用中的微血管:对脉冲氧计的探索

Hui Ma^1,2, Dario Angelone^1,2, Claudia Nunzia Guadagno³

¹Tyndall National Institute, Biophotonics@Tyndall, Cork, Ireland.

Journal of biomedical optics

|December 19, 2024

概括

开发了一种新的固态动态幻影,以克服现有系统的局限性. 这种幻影迅速改变光学特性,使得脉冲氧计等光谱仪器器件的精确校准成为可能.

科学领域:

生物医学光学生物医学光学
光谱仪器仪器仪表仪器仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表仪表
幻影开发幻影开发

背景情况:

动态幻象对于标准化光谱系统至关重要,包括脉冲氧计.
现有的液体幻影的保质期短,设置复杂.
目前的固体幻影面临的挑战是显示干扰,低分辨率和缓慢响应.

研究的目的:

为了开发一个具有快速光学属性控制的固体动态幻影.
为了生成动态的生物信号,用于高级系统校准.
为了克服当前液体和固体动态幻象的局限性.

主要方法:

通过液晶显示器 (LCD) 调制,实时控制光学吸收特性.
使用光导体将幻影与LCD角依赖隔离.
在多个波长 (940,660,530,455 nm) 中对幻影进行了表征,用于查找表.

主要成果:

合成光聚体显微镜 (PPG) 信号模拟心率从每小时80到120次.
在波长的86%,90%,95%和100%的生成氧和 (SpO2) 水平.
建立了一个具有可控制光学属性的特征动态幻影.

结论:

开发的固态动态幻影可以快速控制光学特性.
它可以模拟各种生物信号以进行校准和验证.
潜在的应用包括校准脉冲氧计,成像和光谱系统.

关键词:

扩散光学是一种扩散光学.动态幻影动态幻影接近红外光谱学近红外光谱学摄影复合体学摄影复合体学摄影复合体学脉冲氧计可以测量脉冲氧.标准化标准化标准化

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相关概念视频

Blood Flow

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.