在胎儿和产后生活中缺少静脉管的生理影响
Shweta Bakhru1, Nageswara Rao Koneti1
1Department of Pediatric Cardiology, Rainbow Children's Heart Institute, Hyderabad, Telangana, India.
Annals of pediatric cardiology
|December 19, 2024
概括
在胎儿循环中缺少静脉管 (ADV) 可能会导致心脏膨胀,在肝外形式,可能导致移植系统性分流 (PSS). 在胎儿心声学期间早期的DV评估对于识别这些风险至关重要.
科学领域:
- 胎儿心脏病学 胎儿心脏病学
- 儿童心脏病学 儿童心脏病学
- 血管生物学 血管生物学
背景情况:
- 静脉管 (DV) 对胎儿的血液循环至关重要.
- 缺席的DV (ADV) 与先天性缺陷,门静脉异常和染色体问题有关.
- 了解ADV对胎儿血液动力学和婴儿结果的影响至关重要.
研究的目的:
- 研究缺席静脉管 (ADV) 对胎儿血液循环的影响.
- 评估患有ADV的婴儿的产后结果.
- 为了确定与ADV相关的潜在并发症.
主要方法:
- 在专业心脏中心进行观察性研究 (2016年8月 - 2020年1月).
- 胎儿心声学用于识别ADV,评估静脉流动,并评估心脏参数.
- 产后评估,包括腹部超声波,CT扫描,以检测移植系统突变 (PSS) 和氨水水平监测.
主要成果:
- 确定了12例ADV病例,其中4例是肝内8例是肝外排水模式.
- 所有ADV患者都表现出心壮病;没有人发展出水.
- 四名患者在产后患有持续的PSS,所有患者都患有无症状的肺高血压;肝内变异没有显示PSS.
结论:
- 建议在胎儿心声学期间对DV进行评估.
- ADV与心血管壮大和潜在的右心扩张有关.
- 额外肝脏ADV构成开发系统端口分流 (PSS) 的风险.
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