相关实验视频
Updated: Aug 6, 2026

08:04
Murine Fetal Echocardiography
Published on: February 15, 2013
在评估小胎儿心脏功能时,二维斑点跟踪回声心脏学的价值
Wen Zhang1,2, Bo Zhang1,2, Ting Wu1,2
1Department of Ultrasonic Medicine, West China Second Hospital of Sichuan University, Chengdu, China.
Quantitative imaging in medicine and surgery
|December 19, 2024
概括
二维斑点跟踪回声心电图 (2D-STE) 评估小胎儿的心脏功能. 结合心内全球纵向应变 (endoGLS) 和动脉脉动指数 (UA-PI),可以更好地预测不良妊娠结果.
科学领域:
- 胎儿心脏病学 胎儿心脏病学
- 围产儿医学 围产儿医学
- 医疗成像医学成像
背景情况:
- 小胎儿包括受孕年龄 (SGA) 和胎儿生长受限 (FGR) 的胎儿,由于负面的子宫内环境,FGR对不良围产期结果的风险更高.
- 胎儿的心脏对不良子宫内条件高度敏感,需要敏感的指标来评估心脏功能和预测小胎儿的怀孕结果.
研究的目的:
- 在小胎儿中使用二维斑点跟踪心声学 (2D-STE) 评估胎儿心脏功能.
- 确定敏感的指标,以预测怀孕年龄小于妊娠年龄 (SGA) 和胎儿生长限制 (FGR) 的胎儿的不良妊娠结果.
主要方法:
- 一项前性队列研究招募了61名小胎儿 (估计体重/腹周小于10个百分点) 和34名妊娠年龄匹配的对照.
- 二维斑点跟踪回声心电图 (2D-STE) 评估左心室缩功能和应变参数,包括喷射分数 (EF) 和各种全局应变 (myoGCS,myoGLS,endoGCS,endoGLS,GRS).
- 对心脏参数,动脉脉动指数 (UA-PI) 和中脑动脉脉动指数 (MCA-PI) 进行了分析,以确定它们对不良妊娠结果的预测性表现.
主要成果:
- 与SGA和对照组相比,FGR胎儿对EF,myoGCS,myoGLS,endoGCS,endoGLS和GRS的绝对值明显较低 (P<0.05).
- SGA胎儿的绝对myoGLS和endoGLS值明显低于对照组 (P<0.05).
- 与单独的参数相比,内心全球纵向应变 (endoGLS) 和动脉脉动指数 (UA-PI) 的组合表明,与单独的参数相比,对不良妊娠结果 (AUC=0.75) 的预测性能优越.
结论:
- 通过2D-STE进行层特异性应变分析是一种敏感的方法,用于评估左心室肌肉变形,并区分FGR和SGA胎儿之间的心脏功能.
- endoGLS和UA-PI的综合参数显示了作为小胎儿不良妊娠结果的新型,更有效的预测因子的潜力.
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