语言配对关联学习横向化 在叶发症中左侧海马硬化 在叶发症
Andy Sitoh1,2, David Weintrob2,3, Jacqueline F I Anderson1
1School of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia.
Epilepsia open
|December 19, 2024
概括
语言配对关联学习 (PAL) 有效地识别左海马硬化症 (HS),补充了传统的单词列表学习任务. 这项研究为患者的临床使用提供了切断分数.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 神经学 神经学
背景情况:
- 左海马硬化症 (HS) 与口头记忆缺陷有关,特别是在单词列表学习中.
- 有证据表明,口头配对关联学习 (PAL) 也可能受到影响,但需要进一步调查.
研究的目的:
- 评估口头PAL在检测左HS中的实用性.
- 为了比较PAL与单词列表学习 (RAVLT) 的有效性.
- 为了确定PAL的临床切断分数,以识别左侧HS.
主要方法:
- 雷听力口语学习测试 (RAVLT) 和PAL成绩的回顾性分析.
- 该研究包括116名患有HS (双边,左边或右边) 的患者.
主要成果:
- 与右HS患者相比,左侧和双侧HS患者在PAL硬对和所有RAVLT指数上表现明显差.
- 在PAL硬对和RAVLT指数中,左侧HS的区分能力很好 (AUC>0.70).
- RAVLT延迟回忆是最强的预测因素 (AUC = 0.87),其次是PAL硬对学习 (0.80) 和延迟 (0.83).
结论:
- 语言配对协同学习 (PAL) 是一种有价值的认知标志物,用于的左海马体完整性.
- PAL提供了补充词汇列表学习的信息,用于诊断左侧HS.
- 衍生出的截止分数可以帮助临床医生解释PAL结果用于左侧HS检测.
更多相关视频
12:09Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
18.0K
09:57Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
2.5K
相关概念视频
Lateralization
304
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
304
Role of Hippocampus in Memory
157
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
157
Higher Mental Functions of the Brain: Language
732
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
732
Cerebral Hemispheres
297
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
297
Association Areas of the Cortex
5.0K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
5.0K
Language and Cognition
322
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
322
