检查周末追赶睡眠和表型年龄加速之间的关系:来自横截面研究的见解
Dongmei Liu1, Chen Wang1, Ben Huang2
1Center of Clinical Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
概括
周末追赶睡眠 (WCS) 可以降低表型衰老加速 (PhenoAgeAccel) 的风险,特别是对于那些平日睡眠不足的人来说. 适度的WCS对平日睡眠7-8小时的人有好处,而较长的WCS对睡眠不足6小时的人有帮助.
科学领域:
- 老年学和衰老研究研究.
- 睡眠科学 睡眠科学
- 生物标志物开发 生物标志物开发
背景情况:
- 现型衰老加速 (PhenoAgeAccel) 是生物衰老的一个关键生物标志物.
- 周末追赶睡眠 (WCS) 对PhenoAgeAccel的影响尚不清楚.
- WCS是一种常见的行为,以抵消平日睡眠债务.
研究的目的:
- 调查周末追赶睡眠 (WCS) 和表型衰老加速 (PhenoAgeAccel) 之间的联系.
- 为了确定WCS是否会根据周日睡眠时间改变PhenoAgeAccel的风险.
主要方法:
- 分析了国家健康和营养检查调查的7,683名参与者的数据.
- 计算WCS持续时间作为周末和周日睡眠时间之间的差异.
- 多变量逻辑回归和子组分析,以评估WCS和PhenoAgeAccel之间的关系.
主要成果:
- 周末追赶睡眠 (WCS) 与变化的PhenoAgeAccel风险有关,这取决于WCS数量和周日睡眠模式.
- 0-1小时的WCS显示PhenoAgeAccel的几率明显较低 (OR=0.80),特别是在工作日睡眠7-8小时 (OR=0.67).
- 周日睡眠时间少于6小时的个人经历了超过2小时的WCS (OR=0.65) 的PhenoAgeAccel几率降低.
结论:
- 周末追赶睡眠 (WCS) 与表型年龄加速 (PhenoAgeAccel) 的可能性降低有关.
- 对于平日睡眠不足的人来说,益处最为明显,特别是那些睡眠时间少于6小时或7-8小时的人.
- 在特定的睡眠不足人群中,WCS可能是一个可行的策略来缓解衰老加速.
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